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Jorge
Reis-Filho
Chief of AI for Science Innovation, Enterprise AI Unit
AstraZeneca
Jorge is Chief of AI for Science Innovation within the Enterprise AI Unit at AstraZeneca, where he leads the application of advanced AI, foundation models, and agentic systems to transform drug discovery and clinical development. Previously, he served as Chief AI and Data Scientist for Oncology R&D and VP of Cancer Biomarker Development, driving clinically validated biomarker innovation. With deep expertise spanning molecular pathology, genomics, bioinformatics, and AI, he has held senior roles at Memorial Sloan Kettering Cancer Center and advised leading biotech and investment organizations.
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05 June 2025 09:00 - 09:30
Architecting GenAI systems that can evolve in production
Most GenAI systems are easy to build and hard to change. Once in production, small updates - prompt changes, new tools, model swaps, data source updates - can introduce unexpected regressions. Hidden coupling across components, brittle orchestration, and unclear interfaces make systems increasingly fragile as they grow. This session focuses on the architectural failure modes that cause GenAI systems to calcify over time. We’ll examine how teams design for change in production by introducing clear boundaries, versioned components, and modular execution paths. The emphasis is on patterns that support safe iteration, controlled deployment, and long-lived systems rather than one-off prototypes.