In this keynote, our speakers will provide an overview of the GOSH DRIVE team’s journey towards leveraging the capabilities of AI technologies to enrich our data resources. We will then focus on the potential capabilities of Large Language Models (LLMs) within the paediatric healthcare setting. Large volumes of data are recorded as part of routine healthcare, but often much of this data remains unused for the purposes of research and developing our capabilities as it is simply not feasible to manually extract all the data. In this session we will discuss how we have been able to perform high quality, reliable and accurate data extraction from documents, by leveraging the power of LLMs. We will share our experience and insights towards deploying "smaller" general-purpose LLMs for extracting relevant information that is present within unstructured texts and their enhanced zero-shot capabilities with the help of hand-crafted prompts. We will also share generalisability across a number of use-cases.